Metals have been used for health and healing for thousands of years. Today, the use of metal complexes as medicinal substances is becoming more and more significant as inorganic chemistry evolves. This book, Metals in Medicine, set in two volumes, provides detailed information on and applications of metal-containing compounds that function as essential tools in medical science for the imaging and diagnosis of disease as well as for the prevention and treatment of many diseases.

Volume 1: Metals for Tissue Engineering and Pharmaceutical Applications introduces metallodrugs and their applications in the biomedical field, including for tissue engineering, drug delivery, bioimaging, biosensing, and bone tissue engineering. Volume 2: Metallic Nanoparticles for Biomedical Applications illustrates the possible applications of different types of metal-based drugs in the pharmaceutical and biomedical fields.

In Volume 1, a curated collection of the latest medicinal and inorganic chemical research featuring metals for medicinal applications is presented. The book covers the use of metallic foams, metallic nanocarriers, metal organic frameworks of bioimaging and biosensing application, metallic scaffolds for tissue engineering, and much more. The volume presents the valuable therapeutic and diagnostic properties of metallic drugs, connecting the fields of inorganic chemistry and medicine.

Volume 2 deals with the application of particular metal-active drugs for disease treatment and diagnosis. It presents the compounds/complexes that have been found to be promising for potential therapeutic use along with their properties and the diseases against which they could be effective. It explores the application of gold and silver nanoparticles for tissue engineering as well as their role in cancer therapy. In addition, it employs real-life applications of metallic drugs that include gold- and zinc-based nanosystems in cancer therapy, zinc oxide in disease diagnosis, gold/silver nanoparticles for tissue engineering and biomedical applications, palladium in photothermal therapy for cancer, etc. This volume gives a comprehensive and thorough analysis of the use of metal complexes in medicine.

This two-volume resource will serve as a reference for professionals, faculty and graduate students, and postdoctoral researchers in the fields of materials science, biomedical engineering, and metallo-engineering. It is a valuable resource for academic and industrial scientists working in inorganic chemistry, medicinal chemistry, and drug discovery.

Sonali Sundram, MPharm, is Assistant Professor in the School of Medical and Allied Sciences at Galgotias University, Greater Noida, Uttar Pradesh, India. Previously, she worked as a research scientist on a project of the Indian Council of Medical Research (ICMR) at King George’s Medical University, Lucknow, India. After that, she joined BBDNIIT (Babu Banarasi Das Northern India Institute of Technology), Lucknow. Her PhD (Pharmacy) work was in Neurodegeneration and Nanoformulation. Her areas of interest include neurodegeneration, clinical research, and artificial intelligence. She has authored and edited more than 15 books (published by Wiley, CRC Press/Taylor and Francis, IOP Publishing, Apple Academic Press/Taylor and Francis, Springer Nature and River Publisher) and has organized more than 15 national and international seminars, conferences, and workshops. She has more than eight patents, both national and international, to her credit. She has published six SCI-indexed manuscripts (cumulative impact factor: 20.71) with reputed international publishers. She has delivered oral presentations at international conferences organized in different European countries. She completed both her BPharm and MPharm (Pharmacology) at Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India.

Rishabha Malviya, PhD, has 11 years of research experience and is presently working as Associate Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India. His areas of interest include formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 150 research/review papers for national/international journals of repute. He has over 50 patents to his name and many publications in reputed national and international journals (with a total of 91 cumulative impact factor). He has also received an Outstanding Reviewer Award from Elsevier. He has edited books (Wiley, Springer Nature, CRC Press/Taylor and Francis, Apple Academic Press, River Publisher, Lambert, etc.) and authored 15 book chapters. His name has been included in the Stanford University’s World’s Top 2% Scientists, 2020 by Elsevier BV and Stanford University. He is a reviewer, editor, and editorial board member for more than 50 national and international journals. He was an invited author for the magazine Atlas of Science as well as a pharma magazine dealing with the B2B industry, Ingredients South Asia. He completed his BPharm at Uttar Pradesh Technical University and MPharm (Pharmaceutics) at Gautam Buddha Technical University, Lucknow, Uttar Pradesh, India. His PhD (Pharmacy) work was in novel formulation development techniques.

GSN Koteswara Rao, PhD, MPharm, MBA, is Professor and Head of the Department of Pharmaceutics at SPPSPTM, SVKM’s NMIMS University, Mumbai, India. He has 15 years of academic, research, and administrative experience. He has received several awards and is also a recipient of a UGC fellowship. He presented his research outcomes at the American Association of Pharmaceutical Scientists (AAPS) at San Diego, California, USA, in 2017. He has published more than 75 research papers in reputed national and international journals. In addition, he has also published 10 books and book chapters with international publishers such as Elsevier, Springer, and Wiley. He has participated in more than 80 national and international conferences, seminars, symposia, workshops, and faculty development programs. His areas of research interest include formulation design, development of novel drug delivery systems, bioanalytical method development, in vitro and vivo studies, biopharmaceutical evaluation, and pharmacokinetic-pharmacodynamic drug interactions.