The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO. Conventional drugs, while providing symptomatic relief, have often fallen short of halting the relentless progression of this neurodegenerative disorder. This new two-volume set represents a collective effort to delve into the potential of nature’s pharmacopeia in our battle against Alzheimer’s disease.

Volume 2: Strategies to Unlock the Brain’s Fortress offers a comprehensive exploration into the cutting-edge strategies for the pursuit of effective Alzheimer’s management. It first offers a holistic exploration of nutraceuticals and their pivotal role in managing Alzheimer’s disease, serving as a guide to the diverse array of neuro-nutraceuticals and providing insights into their mechanisms, efficacy, and potential integration into holistic Alzheimer’s management strategies. The book looks at natural antioxidant therapeutics, natural steroidal phytopharmaceuticals and Terpenes (aromatic compounds found in many plants), anti-apoptotic natural products, polysaccharides, neuro-protective role of vitamin D, and non-flavonoidal agents for the effective treatment of Alzheimer’s. Recent developments and advancements in the delivery of nutraceuticals are explored as well, looking at nanotechnology and advanced drug delivery systems for therapeutic interventions.

Volume 1: Targeting Key Pathological Pathways covers the pathophysiology and diagnosis of Alzheimer’s disease, its connection to gut microbiome, drug-induced Alzheimer’s disease, and more, also discussing the vast potential of nutraceuticals in managing Alzheimer’s disease. It explores a plethora of medicinal plants and their secondary metabolites that show promise in treating this devastating condition.

Together, these volumes not only reflect the current state of knowledge but also pave the way for future exploration in the field.

Varinder Singh, PhD, is an Assistant Professor of Pharmaceutical Sciences and Technology at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India. He is well versed in the fields of natural product chemistry (isolation and characterization of bioactive natural compounds), drug discovery, and pharmacology. He has a strong record of publications in high-impact peer-reviewed journals, with many of his papers cited extensively in the field of natural products.

Amit Kumar, PhD, is an Associate Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. He has 12 years of teaching and research experience and has published more than 20 research articles in international journals. He has also filed three patents. His area of research includes neuroprotective drug development and elucidating pathological features of diseases.

Parul Sood, PhD, is an Associate Professor at Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India. She has more than 14 years of professional experience in teaching and research. Her area of specialization and research is exploring herbal plants for the treatment of various neurological disorders including, Alzheimer’s disease, as well as pharmacognostical and phytochemical evaluation, and standardization of herbal drugs and herbal drug formulation development.